- Authors:
-
- Petersen, Line Kirkeby ;
-
Christensen, Kaare
;
Close
0000-0002-5429-5292
Epidemiology, Biostatistics and Biodemography, Department of Public Health, Faculty of Health Sciences, University of Southern Denmark - Kragstrup, Jakob
- Subtitle:
- A review of observational studies and RCTs on cholesterol and mortality in 80+-year olds
- DOI:
- 10.1093/ageing/afq129
- Abstract:
- People aged 80 or older are the fastest growing population in high-income countries. One of the most common causes of death among the elderly is the cardiovascular disease (CVD). Lipid-lowering treatment is common, e.g. one-third of 75-84-year-old Swedes are treated with statins. The assumption that hypercholesterolaemia is a risk factor at the highest ages seems to be based on extrapolation from younger adults. A review of observational studies shows a trend where all-cause mortality was highest when total cholesterol (TC) was lowest ('a reverse J-shaped' association between TC and all-cause mortality). Low TC (
- Type:
- Journal article
- Language:
- English
- Published in:
- Age and Ageing, 2010, Vol 39, Issue 6, p. 674-80
- Main Research Area:
- Medical science
- Publication Status:
- Published
- Review type:
- Peer Review
- Submission year:
- 2010
- Scientific Level:
- Scientific
- ID:
- 112377825
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