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H-Y antibody titers are increased in unexplained secondary recurrent miscarriage patients and associated with low male : female ratio in subsequent live births

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Authors:
  • Nielsen, H S ;
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    unknown
  • Wu, F ;
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    unknown
  • Aghai, Z ;
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    unknown
  • Steffensen, R ;
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    Klinisk Immunologi, Aalborg Sygehus, Faculty of Health Sciences, Aarhus University, Aarhus University
  • van Halteren, A G ;
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    unknown
  • Spierings, E ;
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    unknown
  • Christiansen, O B ;
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    Gynækologisk-Obstetrisk Afdeling, Aalborg Sygehus, Faculty of Health Sciences, Aarhus University, Aarhus University
  • Miklos, D ;
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    unknown
  • Goulmy, E
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    unknown
DOI:
10.1093/humrep/deq242
Abstract:
The birth of a boy is significantly more common than a girl prior to secondary recurrent miscarriage (SRM) and is associated with a poorer chance of a subsequent live birth. Children born after SRM are more likely to be girls. High-titer antisera specific for male antigens (H-Y) have been shown to arrest development of male bovine embryos efficiently. We consequently questioned the role of H-Y antibodies in women with SRM.
Type:
Journal article
Language:
English
Published in:
Human Reproduction (oxford, England), 2010, Vol 25, Issue 11, p. 2745-52
Keywords:
Journal Article; Research Support, Non-U.S. Gov't
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2010
Scientific Level:
Scientific
ID:
112346057

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