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Lamotrigine versus lithium as maintenance treatment in bipolar I disorder: an open, randomized effectiveness study mimicking clinical practice. The 6th trial of the Danish University Antidepressant Group (DUAG-6)

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Authors:
  • Licht, Rasmus W ;
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    The Department of General Psychiatry, Faculty of Health Sciences, Aarhus University, Aarhus University
  • Nielsen, Jannie N ;
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    Specialeuddannelsen i almen medicin, Faculty of Health Sciences, Aarhus University, Aarhus University
  • Gram, Lars F ;
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    unknown
  • Vestergaard, Per ;
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    The Department of General Psychiatry, Faculty of Health Sciences, Aarhus University, Aarhus University
  • Bendz, Hans
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    unknown
DOI:
10.1111/j.1399-5618.2010.00836.x
Abstract:
In industry-generated pivotal studies, lamotrigine has been found to be superior to placebo and comparable to lithium in the maintenance treatment of bipolar I disorder. Here, we directly compared lamotrigine to lithium under conditions similar to clinical routine conditions.
Type:
Journal article
Language:
English
Published in:
Bipolar Disorders, 2010, Vol 12, Issue 5, p. 483-93
Keywords:
Adult; Antimanic Agents; Bipolar Disorder; Confidence Intervals; Female; Humans; Lithium Compounds; Male; Proportional Hazards Models; Treatment Outcome; Triazines
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2010
Scientific Level:
Scientific
ID:
112138821

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