possible implications for individualized drug therapy
The objective of the present study was to identify structural variants of drug target-encoding genes on a genome-wide scale. We also aimed at identifying drugs that are potentially amenable for individualization of treatments based on knowledge about structural variation in the genes encoding their targets.
Pharmacogenetics and Genomics, 2012, Vol 22, Issue 7, p. 471-83
Journal Article; DNA Copy Number Variations; Databases, Factual; Genetic Variation; Genome, Human; Genomics; Humans; Pharmaceutical Preparations; Pharmacogenetics; Proteins; United States; United States Food and Drug Administration