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A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions

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Authors:
  • Lund, Lasse Wegener ;
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    Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark
  • Schmiegelow, Kjeld ;
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    Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark
  • Rechnitzer, Catherine ;
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    Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark
  • Johansen, Christoffer
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    unknown
DOI:
10.1002/pbc.22883
Abstract:
High survival rates after childhood cancer raise attention to possible psychosocial late effects. We focus on predictors of psychosocial outcomes based on diagnosis, treatment, demography, somatic disease, and methodological problems. Overall, survivors evaluate their health-related quality of life to be normal or even better than controls, although virtually all diagnostic subgroups report psychosocial impairment. Central nervous system tumor survivors have significant psychosocial problems. Negative outcomes were associated with cranial radiation therapy, female gender, and young age at diagnosis. Significant methodological problems hamper current knowledge. Systematic registration of psychosocial and somatic problems at diagnosis and prospectively through protocols is needed.
Type:
Journal article
Language:
English
Published in:
Pediatric Blood and Cancer, 2011, Vol 56, Issue 4, p. 532-43
Keywords:
Journal Article; Research Support, Non-U.S. Gov't; Adult; Central Nervous System Neoplasms; Child; Educational Status; Employment; Health Status; Humans; Life Style; Marriage; Mental Disorders; Neoplasms; Quality of Life; Socioeconomic Factors; Survivors
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2011
Scientific Level:
Scientific
ID:
163545030

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