1 Department of Clinical Physiology and Nuclear Medicine, Centre for Functional and Diagnostic Imaging and research, Amager and Hvidovre Hospital, The Capital Region of Denmark2 Centre for Functional and Diagnostic Imaging and research, Amager and Hvidovre Hospital, The Capital Region of Denmark3 Klinik for Klinisk Fysiologi, Nuklearmedicin og PET, Diagnostisk Center, Rigshospitalet, The Capital Region of Denmark4 Clinical Physiology and Nuclear Medicine, Herlev and Gentofte Hospital, The Capital Region of Denmark
Reliable and valid body composition assessment is important in both clinical and research settings. A multitude of methods and techniques for body composition measurement exist, all with inherent problems, whether in measurement methodology or in the assumptions upon which they are based. This review is focused on currently applied methods for in vivo measurement of body composition, including densitometry, bioimpedance analysis, dual-energy X-ray absorptiometry, computed tomography (CT), magnetic resonance techniques and anthropometry. Multicompartment models including quantification of trace elements by in vivo neutron activation analysis, which are regarded as gold standard methods, are also summarized. The choice of a specific method or combination of methods for a particular study depends on various considerations including accuracy, precision, subject acceptability, convenience, cost and radiation exposure. The relative advantages and disadvantages of each method are discussed with these considerations in mind.
Clinical Physiology and Functional Imaging, 2015, Vol 35, Issue 2, p. 81-97