Genome-wide association and biological pathway analysis for milk-fat composition in Danish Holstein and Danish Jersey cattle

Bart Buitenhuis; Luc L G Janss; Nina Aagaard Poulsen; Lotte Bach Larsen; Mette Krogh Larsen; Peter Sørensen

doi:10.1186/1471-2164-15-1112

Genome-wide association and biological pathway analysis for milk-fat composition in Danish Holstein and Danish Jersey cattle

Authors:

Buitenhuis, Bart ;
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Department of Molecular Biology and Genetics - Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Science and Technology, Aarhus University
Janss, Luc L G ;
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Department of Molecular Biology and Genetics - Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Science and Technology, Aarhus University
Poulsen, Nina Aagaard ;
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Department of Food Science - Food Chemistry and Technology, Department of Food Science, Science and Technology, Aarhus University
Larsen, Lotte Bach ;
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Department of Food Science - Food Chemistry and Technology, Department of Food Science, Science and Technology, Aarhus University
Larsen, Mette Krogh ;
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unknown
Sørensen, Peter
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Department of Molecular Biology and Genetics - Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Science and Technology, Aarhus University

DOI:

10.1186/1471-2164-15-1112

Abstract:

The milk fat profile of the Danish Holstein (DH) and Danish Jersey (DJ) show clear differences. Identification of the genomic regions, genes and biological pathways underlying the milk fat biosynthesis will improve the understanding of the biology underlying bovine milk fat production and may provide new possibilities to change the milk fat composition by selective breeding. In this study a genome wide association scan (GWAS) in the DH and DJ was performed for a detailed milk fatty acid (FA) profile using the HD bovine SNP array and subsequently a biological pathway analysis based on the SNP data was performed

Type:

Journal article

Language:

English

Published in:

B M C Genomics, 2014, Vol 15, Issue 1112, p. 1-11

Main Research Area:

Science/technology

Publication Status:

Published

Review type:

Peer Review

Submission year:

2014

Scientific Level:

Scientific

ID:

273383916

Genome-wide association and biological pathway analysis for milk-fat composition in Danish Holstein and Danish Jersey cattle

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