1 Erler Group, BRIC Research Groups, BRIC, Københavns Universitet2 Erler Group, BRIC, Faculty of Health and Medical Sciences, Københavns Universitet3 Erler Group, BRIC, Faculty of Health and Medical Sciences, Københavns Universitet
Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.
Journal review article
Future Oncology, 2014, Vol 10, Issue 9, p. 1709-17