Schwensen, Jakob F3; Menné, Torkil4; Veien, Niels K4; Funding, Anne T4; Avnstorp, Christian4; Osterballe, Morten4; Andersen, Klaus Ejner6; Paulsen, Evy7; Mørtz, Charlotte G7; Sommerlund, Mette4; Danielsen, Anne4; Andersen, Bo L4; Thormann, Jens4; Kristensen, Ove4; Kristensen, Berit4; Vissing, Susanne4; Nielsen, Niels H4; Thyssen, Jacob P4; Johansen, Jeanne D4
1 Dermato-venerology and Allergy Centre, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU2 ORCA, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU3 Copenhagen University Hospital4 unknown5 CIMT- Centre for Innovative Medical Technology, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU6 CIMT- Centre for Innovative Medical Technology, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU7 Dermato-venerology and Allergy Centre, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU
results from a multicentre study from the Danish Contact Dermatitis Group (2003-2012)
BACKGROUND: Blue-collar workers have a high risk of occupational contact dermatitis, but epidemiological studies are scarce. OBJECTIVES: To investigate allergic contact dermatitis in blue-collar workers with dermatitis registered by the Danish Contact Dermatitis Group. METHODS: A retrospective analysis of patch test data from 1471 blue-collar workers and 1471 matched controls tested between 2003 and 2012 was performed. A logistic regression was used to test for associations. RESULTS: The blue-collar workers often had occupational hand dermatitis (p < 0.001). Atopic dermatitis was less commonly observed among blue-collar workers (19.6%) than among controls (23.9%) (p = 0.005). Allergens with a statistically significant association with the occupational group of blue-collar workers were epoxy resins, methyldibromo glutaronitrile, 2-bromo-2-nitro-1,3-propanediol, potassium dichromate, and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI). The following occupations were additionally identified as risk factors for contact sensitization to MCI/MI and MI, epoxy resins, and potassium dichromate, respectively: painting, construction work, and tile setting/terrazzo work. CONCLUSION: Contact allergy is a major problem among blue-collar workers. The data indicate a healthy worker effect among blue-collar workers diagnosed with dermatitis, as blue-collar workers were diagnosed significantly less often with atopic dermatitis than were controls.
Contact Dermatitis, 2014, Vol 71, Issue 6, p. 348-355