Schwensen, Jakob F3; Menné, Torkil3; Veien, Niels K4; Funding, Anne T4; Avnstorp, Christian3; Østerballe, Morten3; Andersen, Klaus E5; Paulsen, Evy3; Mørtz, Charlotte G3; Sommerlund, Mette7; Danielsen, Anne3; Andersen, Bo L3; Thormann, Jens3; Kristensen, Ove3; Kristensen, Berit6; Vissing, Susanne3; Nielsen, Niels H8; Thyssen, Jacob P3; Johansen, Jeanne D3
1 Department of Clinical Medicine - The Department of Dermatology and Venereology, Department of Clinical Medicine, Health, Aarhus University2 Department of Physics and Astronomy, Science and Technology, Aarhus University3 unknown4 The Department of Dermatology and Venereology, Faculty of Health Sciences, Aarhus University, Aarhus University5 Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark.6 Department of Animal Research Facilities, Faculty of Agricultural Sciences, Aarhus University, Aarhus University7 Department of Clinical Medicine - The Department of Dermatology and Venereology, Department of Clinical Medicine, Health, Aarhus University8 Department of Physics and Astronomy, Science and Technology, Aarhus University
results from a multicentre study from the Danish Contact Dermatitis Group (2003-2012)
BACKGROUND: Blue-collar workers have a high risk of occupational contact dermatitis, but epidemiological studies are scarce. OBJECTIVES: To investigate allergic contact dermatitis in blue-collar workers with dermatitis registered by the Danish Contact Dermatitis Group. METHODS: A retrospective analysis of patch test data from 1471 blue-collar workers and 1471 matched controls tested between 2003 and 2012 was performed. A logistic regression was used to test for associations. RESULTS: The blue-collar workers often had occupational hand dermatitis (p < 0.001). Atopic dermatitis was less commonly observed among blue-collar workers (19.6%) than among controls (23.9%) (p = 0.005). Allergens with a statistically significant association with the occupational group of blue-collar workers were epoxy resins, methyldibromo glutaronitrile, 2-bromo-2-nitro-1,3-propanediol, potassium dichromate, and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI). The following occupations were additionally identified as risk factors for contact sensitization to MCI/MI and MI, epoxy resins, and potassium dichromate, respectively: painting, construction work, and tile setting/terrazzo work. CONCLUSION: Contact allergy is a major problem among blue-collar workers. The data indicate a healthy worker effect among blue-collar workers diagnosed with dermatitis, as blue-collar workers were diagnosed significantly less often with atopic dermatitis than were controls.
Contact Dermatitis, 2014, Vol 71, Issue 6, p. 348-55