de Sousa, M V3; Fukui, R3; Krustrup, Peter7; Pereira, R M R4; Silva, P R S5; Rodrigues, A C6; de Andrade, J L6; Hernandez, A J5; da Silva, M E R3
1 Integrated Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, Københavns Universitet2 Center for Holdspil og Sundhed, Department of Nutrition, Exercise and Sports, Faculty of Science, Københavns Universitet3 Laboratory of Medical Investigation, LIM-18, Endocrinology Division, School of Medicine, University of São Paulo, São Paulo, Brazil.4 Bone Metabolism Laboratory, LIM-17, Rheumatology Division, School of Medicine, University of São Paulo, São Paulo5 Department of Orthopeadics and Traumatology, University of São Paulo, São Paulo6 Echocardiography Laboratory, Institute of Radiology, School of Medicine, University of São Paulo, São Paulo7 Integrated Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, Københavns Universitet
We evaluated the effects of recreational football training combined with calorie-restricted diet (football + diet) vs calorie-restricted diet alone (diet) on aerobic fitness, lipid profile, and insulin resistance indicators in type 2 diabetes (T2D) patients. Forty-four T2D patients aged 48-68 years (27 females, 17 males) were randomly allocated to the football + diet group (FDG; n = 22) or to the diet group (DG; n = 22), of whom 19 FDG and 15 DG subjects completed the study. The football training was performed for 3 × 40 min/week for 12 weeks. Dual-energy X-ray absorptiometry scanning, treadmill testing, and fasting blood samplings were performed pre and post-intervention. After 12 weeks, maximal oxygen uptake (VO2max ) was elevated (P < 0.05) by 10 ± 4% in FDG but not in DG (-3 ± 4%, P < 0.05). After 12 weeks, reductions in blood triglycerides (0.4 ± 0.1 mmol/L), total cholesterol (0.6 ± 0.2 mmol/L), low-density lipoprotein, and very low-density lipoprotein levels were observed only in FDG. Fat mass decreased (P < 0.05) by 3.4 ± 0.4 kg in FDG and 3.7 ± 0.4 kg in DG. The lower (P < 0.05) glucagon and homeostatic model assessment of insulin resistance indicated an improvement in insulin sensitivity in FDG. In conclusion, football combined with restricted diet was effective in enhancing VO2max , reducing total cholesterol and triglycerides, and increasing insulin sensitivity, potentially providing better tools for the prevention of T2D complications than diet alone.
Scandinavian Journal of Medicine and Science in Sports, 2014, Vol 24, Issue Suppl. 1, p. 57-65