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Enhancing brain lesions after endovascular treatment of aneurysms

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Authors:
  • Cruz, J P ;
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    unknown
  • Marotta, T ;
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    unknown
  • O'Kelly, C ;
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    unknown
  • Holtmannspötter, M ;
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    Diagnostic Radiology, Department of, Centre of Diagnostic Investigations, Rigshospitalet, The Capital Region of Denmark
  • Saliou, G ;
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    unknown
  • Willinsky, R ;
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    unknown
  • Krings, T ;
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    unknown
  • Agid, R
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    unknown
DOI:
10.3174/ajnr.A3976
Abstract:
Complications of endovascular therapy of aneurysms mainly include aneurysm rupture and thromboembolic events. The widespread use of MR imaging for follow-up of these patients revealed various nonvascular complications such as aseptic meningitis, hydrocephalus, and perianeurysmal brain edema. We present 7 patients from 5 different institutions that developed MR imaging-enhancing brain lesions after endovascular therapy of aneurysms, detected after a median time of 63 days. The number of lesions ranged from 4-46 (median of 10.5), sized 2-20 mm, and were mostly in the same vascular territory used for access. Three patients presented with symptoms attributable to these lesions. After a median follow-up of 21.5 months, the number of lesions increased in 2, was stable in 1, decreased in 3, and disappeared in 1. The imaging and clinical characteristics suggested a foreign body reaction. We could find no correlation to a specific device, but a possible source may be the generic hydrophilic coating.
Type:
Journal article
Language:
English
Published in:
Ajnr. American Journal of Neuroradiology, 2014, Vol 35, Issue 10, p. 1954-8
Keywords:
Adult; Brain; Brain Diseases; Embolization, Therapeutic; Endovascular Procedures; Female; Humans; Hydrocephalus; Intracranial Aneurysm; Male; Middle Aged; Journal Article
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2015
Scientific Level:
Scientific
ID:
267901339

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