Hjorth, P.6; Davidsen, A. S.3; Kilian, R.4; Skrubbeltrang, C.5
1 Infrastructure Department, IT Services, Central Administration, SDU2 Psychiatry Region Syddanmark, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU3 University of Copenhagen4 Ulm University5 Aalborg Hospital6 Psychiatry Region Syddanmark, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU
Objective: Overweight and obesity are generally found among patients with schizophrenia. This may lead to serious implications for health and wellbeing. The aim was to review controlled intervention studies on reducing overweight/obesity and/or reducing physical illness in patients with schizophrenia. Method: A systematic literature search was carried out in the bibliographic databases PubMed (MEDLINE), Embase (Ovid), PsycInfo (Ovid) and Cinahl (Ebsco). We included all randomised and non-randomised clinically controlled studies that compared a non-pharmacological intervention, aimed at weight reduction and/or reducing physical illness, with standard care for patients with schizophrenia. Results: All 1713 references were evaluated for inclusion in the review. Twenty-three met the inclusion criteria and were categorised into four subgroups according to tested interventions: diet, exercise and cognitive behavioural therapy, or mixed combinations of the three. In this review, interventions showed efficacy in reducing weight and improving physical health parameters confirming that physical health improvement was possible in patients with schizophrenia. Conclusion: The included studies indicate that the interventions reduced weight and improved physical health parameters in patients with schizophrenia.