Tom, S8; Galbraith, J C7; Valiquette, L7; Jacobsson, G7; Collignon, P7; Schønheyder, H C2; Søgaard, M2; Kennedy, K J7; Knudsen, J D7; Ostergaard, C7; Lyytikäinen, O7; Laupland, K B7
1 Department of Clinical Medicine, The Faculty of Medicine, Aalborg University, VBN2 The Faculty of Medicine, Aalborg University, VBN3 Aalborg University Hospital, The Faculty of Medicine, Aalborg University, VBN4 Klinik Diagnostik, The Faculty of Medicine, Aalborg University, VBN5 Klinisk Mikrobiologi, The Faculty of Medicine, Aalborg University, VBN6 University of Calgary7 unknown8 University of Calgary
Lethal outcomes can be expressed as a case fatality ratio (CFR) or as a mortality rate per 100 000 population per year (MR). Population surveillance for community-onset methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) Staphylococcus aureus bacteraemia was conducted in Canada, Australia, Sweden and Denmark to evaluate 30-day CFR and MR trends between 2000 and 2008. The CFR was 20.3% (MSSA 20.2%, MRSA 22.3%) and MR was 3.4 (MSSA 3.1, MRSA 0.3) per 100 000 per year. Although MSSA CFR was stable the MSSA MR increased; MRSA CFR decreased while its MR remained low during the study. Community-onset S. aureus bacteraemia, particularly MSSA, is associated with major disease burden. This study highlights complementary information provided by evaluating both CFR and MR.
Clinical Microbiology and Infection, 2014, Vol 20, Issue 10