Electroporation is increasingly being used for delivery of chemotherapy to tumors. Likewise, gene delivery by electroporation is rapidly gaining momentum for both vaccination purposes and for delivery of genes coding for other therapeutic molecules, such as chronic diseases or cancer. This chapter describes how gene therapy may be performed using electric pulses to enhance uptake and expression.
Methods in Molecular Biology (clifton, N.j.), 2014, Vol 1121, p. 241-6
Clinical Trials as Topic; Electroporation; Gene Transfer Techniques; Genetic Therapy; Humans; Journal Article