Wohlfahrt-Veje, C4; Tinggaard, J1; Winther, K3; Mouritsen, A1; Hagen, C P2; Mieritz, M G1; de Renzy-Martin, K T4; Boas, M5; Petersen, J H1; Main, K M1
1 Department of Growth and Reproduction, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark2 Endokrinologisk Afdeling I, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark3 Department of Clinical Biochemistry, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark4 unknown5 Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark
agreement of BMI, waist circumference, skinfolds with dual X-ray absorptiometry
BACKGROUND/OBJECTIVES: Total body fat percentage (%BF) evaluated by dual energy X-ray absorptiometry (DXA) scans (DXA %BF) is widely recognized as a precise measure of fatness. We aimed to establish national reference curves for DXA %BF, %BF calculated from skinfolds (SF %BF) and waist circumference (WC) in healthy children, and to compare agreement between the different methods. SUBJECTS/METHODS: Based on 11 481 physical examinations (anthropometry) and 1200 DXA scans from a longitudinal cohort of Danish children (n=2647), we established reference curves (LMS-method) for SF %BF, WC (birth to 14 years) and DXA %BF (8-14 years). Age- and sex-specific Z-scores for body mass index (BMI), WC and SF %BF were compared. Sensitivity and specificity were calculated for agreement of WC, SF %BF and BMI with DXA %BF to identify obese children (>+1 s.d.). RESULTS: %BF differed with age, sex, pubertal stage and social class. SF %BF correlated strongly with DXA %BF (r=0.86). BMI and WC also correlated positively with DXA %BF (Z-scores; r= 0.78 and 0.69). Sensitivity and specificity were 79.5 and 93.8 for SF %BF, 75.9 and 90.3 for BMI and 59.2 and 95.4 for WC. CONCLUSIONS: SF %BF showed the highest correlation and best agreement with DXA %BF in identifying children with excess fat (+1 s.d.).
European Journal of Clinical Nutrition, 2014, Vol 68, Issue 6, p. 664-70
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Absorptiometry, Photon; Adipose Tissue; Adolescent; Age Factors; Anthropometry; Body Composition; Body Mass Index; Child; Child, Preschool; Denmark; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Pediatric Obesity; Puberty; Reference Values; Sensitivity and Specificity; Sex Factors; Skinfold Thickness; Social Class; Waist Circumference