Renal dysfunction is associated with a variety of cardiac alterations including left ventricular (LV) hypertrophy, LV dilation, and reduction in systolic and diastolic function. It is common and associated with an increased mortality risk in heart failure (HF) patients. This study was designed to evaluate whether severe diastolic dysfunction contribute to the increased mortality risk observed in HF patients with renal dysfunction.
B M C Nephrology, 2013, Vol 14, Issue 1, p. 1-8
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't