Genome sequences reveal that our current standard laboratory conditions only support a fraction of the potential secondary metabolism in bacteria. Thus, we must rethink cultivation, detection, and isolation strategies for bacterial secondary metabolites in order to explore the huge, so far uncharacterized chemical potential of these organisms. We are currently investigating the use of natural substrates and co-cultures with commensal bacteria to elicit or alter production of antibacterial compounds in marine bacteria.
Main Research Area:
14th International Symposium on Marine Natural Products, 2013