1 Department of Systems Biology, Technical University of Denmark2 Natural Product Chemistry, Department of Systems Biology, Technical University of Denmark3 Bacterial Ecophysiology and Biotechnology, Department of Systems Biology, Technical University of Denmark4 Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark5 Technical University of Denmark6 University of California7 Bacterial Ecophysiology and Biotechnology, Department of Biotechnology and Biomedicine, Technical University of Denmark
Genome sequences reveal that our current standard laboratory conditions only support a fraction of the potential secondary metabolism in bacteria. Thus, we must rethink cultivation, detection, and isolation strategies for bacterial secondary metabolites in order to explore the huge, so far uncharacterized chemical potential of these organisms. We are currently investigating the use of natural substrates and co-cultures with commensal bacteria to elicit or alter production of antibacterial compounds in marine bacteria.
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14th International Symposium on Marine Natural Products, 2013