Navaratnam, Kate2; Alfirevic, Zarko3; Baker, Philip N3; Gluud, Christian1; Grüttner, Berthold3; Kublickiene, Karolina3; Zeeman, Gerda3; Kenny, Louise C3
1 Copenhagen Trial Unit, Cochranecenteret Rigshospitalet, Rigshospitalet, The Capital Region of Denmark2 University of Liverpool, Liverpool Women's Hospital3 unknown
improved pregnancy outcomes via early detection (IMPROvED)
5% of first time pregnancies are complicated by pre-eclampsia, the leading cause of maternal death in Europe. No clinically useful screening test exists; consequentially clinicians are unable to offer targeted surveillance or preventative strategies. IMPROvED Consortium members have pioneered a personalised medicine approach to identifying blood-borne biomarkers through recent technological advancements, involving mapping of the blood metabolome and proteome. The key objective is to develop a sensitive, specific, high-throughput and economically viable early pregnancy screening test for pre-eclampsia.