Gousiadou, Chrysoula4; Kokubun, Tetsuo5; Gotfredsen, Charlotte Held1; Jensen, Søren Rosendal1
1 Department of Chemistry, Technical University of Denmark2 Organic Chemistry, Department of Chemistry, Technical University of Denmark3 Department of Organic Chemistry, Technical University of Denmark4 Technical University of Denmark5 The Royal Botanic Gardens
From an extract of Manulea corymbosa were isolated four known secoiridoid glucosides (1–4), 10 new monoterpenoid esters of secologanol, namely, manuleosides A–I (5–11, 13, and 14) and dimethyl rhodanthoside A (12), and four new phenylpropanoid esters of carbocyclic iridoid glucosides, manucorymbosides I–IV (15–18). Also, the caffeoyl phenylethanoid glycoside verbascoside was isolated. The presence of secoiridoids apparently derived from loganic acid in the family Scrophulariaceae is unprecedented and greatly unexpected.
Journal of Natural Products, 2014, Vol 77, Issue 3, p. 589-595