Marquardt, Jens U2; Seo, Daekwan2; Andersen, Jesper Bøje3; Gillen, Matthew C2; Kim, Myoung Soo2; Conner, Elizabeth A2; Galle, Peter R2; Factor, Valentina M2; Park, Young Nyun2; Thorgeirsson, Snorri S2
1 Andersen Group, BRIC Research Groups, BRIC, Københavns Universitet2 unknown3 Andersen Group, BRIC Research Groups, BRIC, Københavns Universitet
Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC). However, the sequential molecular alterations driving malignant transformation of the pre-neoplastic lesions are not clearly defined. This lack of information represents a major challenge in the clinical management of patients at risk.
Journal of Hepatology, 2014, Vol 60, Issue 2, p. 346-53