Marquardt, Jens U2; Seo, Daekwan2; Andersen, Jesper Bøje4; Gillen, Matthew C2; Kim, Myoung Soo2; Conner, Elizabeth A2; Galle, Peter R2; Factor, Valentina M2; Park, Young Nyun2; Thorgeirsson, Snorri S2
1 Andersen Group, BRIC Research Groups, BRIC, Københavns Universitet2 unknown3 Andersen Group, BRIC, Faculty of Health and Medical Sciences, Københavns Universitet4 Andersen Group, BRIC, Faculty of Health and Medical Sciences, Københavns Universitet
Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC). However, the sequential molecular alterations driving malignant transformation of the pre-neoplastic lesions are not clearly defined. This lack of information represents a major challenge in the clinical management of patients at risk.
Journal of Hepatology, 2014, Vol 60, Issue 2, p. 346-53