1 Department of Economics and Business Economics, Aarhus BSS, Aarhus University2 Department of Economics and Business Economics - NCRR-National Centre for Register-based Research, Department of Economics and Business Economics, Aarhus BSS, Aarhus University3 unknown4 Undervisning - FSV5 Institut for Klinisk Medicin6 Department of Economics and Business Economics, Aarhus BSS, Aarhus University
a danish nationwide register study
Maternal immune responses and brain-reactive antibodies have been proposed as possible causal mechanisms for schizophrenia and some child psychiatric disorders. According to this hypothesis maternal antibodies may cross the placenta and interact with the developing CNS of the fetus causing future neurodevelopmental disorders. Therefore, we investigated if children of mothers with cancer might be at higher risk of developing psychiatric disorders, with particular focus on small-cell lung cancer, which is known to induce production of antibodies binding to CNS elements.