Roux-en-Y gastric bypass (RYGB) improves glycaemic control in part by increasing postprandial insulin secretion through exaggerated glucagon-like peptide (GLP)-1 release. However, it is unknown whether islet cell responsiveness to i.v. glucose, non-glucose (arginine) and incretin hormones, including GLP-1, is altered.
Diabetologia, 2013, Vol 56, Issue 12, p. 2679-2687
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't