Johnatty, Sharon E3; Beesley, Jonathan3; Gao, Bo3; Chen, Xiaoqing3; Lu, Yi3; Law, Matthew H3; Henderson, Michelle J3; Russell, Amanda J3; Hedditch, Ellen L3; Emmanuel, Catherine3; Fereday, Sian3; Webb, Penelope M3; Goode, Ellen L3; Vierkant, Robert A3; Fridley, Brooke L3; Cunningham, Julie M3; Fasching, Peter A3; Beckmann, Matthias W3; Ekici, Arif B3; Hogdall, Estrid5; Kjaer, Susanne K5; Jensen, Allan6; Hogdall, Claus5; Brown, Robert James (Jim)3; Paul, Jim3; Lambrechts, Sandrina3; Despierre, Evelyn3; Vergote, Ignace3; Lester, Jenny3; Karlan, Beth Y3; Heitz, Florian3; du Bois, Andreas3; Harter, Philipp3; Schwaab, Ira3; Bean, Yukie3; Pejovic, Tanja3; Levine, Douglas A3; Goodman, Marc T3; Camey, Michael E3; Thompson, Pamela J3; Lurie, Galina3; Shildkraut, Joellen3; Berchuck, Andrew3; Terry, Kathryn L3; Cramer, Daniel W3; Norris, Murray D3; Haber, Michelle3; MacGregor, Stuart3; deFazio, Anna3; Chenevix-Trench, Georgia3; Group, Australian Ovarian Cancer Study3
1 Section of Gynaecology, Obstetrics and Paediatrics, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet2 Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet3 unknown4 Department of Public Health, Faculty of Health and Medical Sciences, Københavns Universitet5 Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet6 Department of Public Health, Faculty of Health and Medical Sciences, Københavns Universitet
A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas
ABCB1 encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance. We comprehensively evaluated this gene and flanking regions for an association with clinical outcome in epithelial ovarian cancer (EOC).
Gynecologic Oncology, 2013, Vol 131, Issue 1, p. 8-14
Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease Progression; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; P-Glycoprotein; Paclitaxel; Pharmacogenetics; Polymorphism, Single Nucleotide; Proportional Hazards Models