1 Anaesthesiology, Herlev, Herlev and Gentofte Hospital, The Capital Region of Denmark2 Department of Intensive Care, Abdominal Centre, Rigshospitalet, The Capital Region of Denmark
Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to post-operative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to the NMB rocuronium - which within 1-3 minutes neutralizes the effects of rocuronium. High-dose rocuronium is now an alternative to suxamethonium in acute or short procedures and in a situation, where ventilation/intubating cannot be performed, sugammadex can reverse the rocuronium blockade within minutes.
Ugeskrift for Laeger, 2013, Vol 175, Issue 7, p. 428-32