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Hypercoagulability in response to elevated body temperature and central hypovolemia

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Authors:
  • Meyer, Martin ;
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    unknown
  • Ostrowski, Sisse R ;
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    Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet
  • Overgaard, Flemming Anders ;
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    LUKKET: 2012 Gruppe for efter-videreudannelse, Department of Exercise and Sport Sciences, Faculty of Science, Københavns Universitet
  • Ganio, Matthew S ;
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    unknown
  • Secher, Niels H ;
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    Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet
  • Crandall, Craig G ;
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    unknown
  • Johansson, Pär I
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    unknown
DOI:
10.1016/j.jss.2013.06.012
Abstract:
Coagulation abnormalities contribute to poor outcomes in critically ill patients. In trauma patients exposed to a hot environment, a systemic inflammatory response syndrome, elevated body temperature, and reduced central blood volume occur in parallel with changes in hemostasis and endothelial damage. The objective of this study was to evaluate whether experimentally elevated body temperature and reduced central blood volume (CBV) per se affects hemostasis and endothelial activation.
Type:
Journal article
Language:
English
Published in:
Journal of Surgical Research, 2013, Vol 185, Issue 2, p. 93-100
Keywords:
Journal Article
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2013
Scientific Level:
Scientific
ID:
246954527

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