- Authors:
- DOI:
- 10.1183/09031936.00129312
- Abstract:
- This study aimed to estimate time-trends in the lifetime risk of hospitalisation with exacerbation of chronic obstructive pulmonary disease (COPD) in Denmark.During the period from 1994 to 2008 a register-based cohort study was conducted covering each subject in the entire population of Denmark (5.43 million in 2008).Based on previously validated diagnosis codes, all COPD hospitalisations were identified. Individual look-back periods of 8 years were used to determine first-time hospitalisations. From year 2002 to 2008 all first-time COPD hospitalised subjects aged 30 years and above were identified. The calculation of lifetime risk was based on age- and sex-specific first-time COPD hospitalisation rates and rates of COPD hospitalisation-free survival, assuming them to be calendar time stationary.The study included 23.9 million person-years of risk time and identified 48 959 first-time COPD hospitalisations. For 30-year-olds in Denmark, the lifetime risk of COPD hospitalisation was 12.0% (95% CI 11.9-12.2) for females and 10.9% (95% CI 10.8-11.1) for males. Trends were generally equal in both sexes. During the period from year 2002 to 2008, the rate of first-time COPD hospitalisations decreased, while the survival of never COPD hospitalised subjects increased. In consequence the lifetime risk of COPD hospitalisation remained constant.
- Type:
- Journal article
- Language:
- English
- Published in:
- European Respiratory Journal, 2013, Vol 42, Issue 4, p. 964-971
- Main Research Area:
- Medical science
- Publication Status:
- Published
- Review type:
- Peer Review
- Submission year:
- 2013
- Scientific Level:
- Scientific
- ID:
- 246492000