1 Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark2 Department of Systems Biology, Technical University of Denmark3 Cellular Signal Integration, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark
Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug design and signaling network analysis.
Clinical Pharmacology and Therapeutics, 2013, Vol 94, Issue 6, p. 646-650
Animals; Antineoplastic Combined chemotherapy protocols; Biological markers; Drug design; Individualized medicine; Molecular targeted therapy; Neoplasms; Protein interaction maps; Protein processing; post-translational modifications; Signal transduction; Systems biology