Lancellotti, Patrizio2; Nkomo, Vuyisile T3; Badano, Luigi P3; Bergler, Jutta3; Bogaert, Jan3; Davin, Laurent3; Cosyns, Bernard3; Coucke, Philippe3; Dulgheru, Raluca3; Edvardsen, Thor3; Gaemperli, Oliver3; Galderisi, Maurizio3; Griffin, Brian3; Heidenreich, Paul A3; Nieman, Koen5; Plana, Juan C3; Port, Steven C3; Scherrer-Crosbie, Marielle3; Schwartz, Ronald G3; Sebag, Igal A3; Voigt, Jens-Uwe3; Wann, Samuel3; Yang, Phillip C3
1 Center OUH-Svendborg Sygehus, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU2 Department of Cardiology, GIGA Cardiovascular Sciences, Heart Valve Clinic, University of Liège Hospital, CHU du Sart-Tilman, Liège 4000, Belgium. firstname.lastname@example.org unknown4 Research Unit Afd M Svendborg, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU5 Research Unit Afd M Svendborg, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU
a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography
Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in life expectancy obtained with anti-cancer therapy can be compromised by increased morbidity and mortality associated with its cardiac complications. While radiosensitivity of the heart was initially recognized only in the early 1970s, the heart is regarded in the current era as one of the most critical dose-limiting organs in radiotherapy. Several clinical studies have identified adverse clinical consequences of radiation-induced heart disease (RIHD) on the outcome of long-term cancer survivors. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHD is discussed. Recommendations for the early identification and monitoring of cardiovascular complications of radiotherapy by cardiac imaging are also proposed.
American Society of Echocardiography. Journal, 2013, Vol 26, Issue 9, p. 1013-1032