Bernstein, Jonine L2; Thomas, Duncan C3; Shore, Roy E3; Robson, Mark3; Boice, John D3; Stovall, Marilyn3; Andersson, Michael1; Bernstein, Leslie3; Malone, Kathleen E3; Reiner, Anne S3; Lynch, Charles F3; Capanu, Marinela3; Smith, Susan A3; Tellhed, Lina3; Teraoka, Sharon N3; Begg, Colin B3; Olsen, Jorgen H3; Mellemkjaer, Lene3; Liang, Xiaolin3; Diep, Anh T3; Borg, Ake3; Concannon, Patrick3; Haile, Robert W3
1 Onkologisk Klinik, Finsencentret, Rigshospitalet, The Capital Region of Denmark2 Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Bernstej@mskcc.org3 unknown
a WECARE study report
Women with germline BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at very high risk of developing breast cancer, including asynchronous contralateral breast cancer (CBC). BRCA1/BRCA2 genes help maintain genome stability and assist in DNA repair. We examined whether the risk of CBC associated with radiation treatment was higher among women with germline BRCA1/BRCA2 mutations than among non-carriers.
European Journal of Cancer (oxford, England : 1990), 2013, Vol 49, Issue 14, p. 2979-85