Brodin, Nils Patrik4; Vogelius, Ivan R.2; Bjørk-Eriksson, Thomas2; Munck af Rosenschöld, Per Martin5
1 Biocomplexity, The Niels Bohr Institute, Faculty of Science, Københavns Universitet2 unknown3 Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet4 Biocomplexity, The Niels Bohr Institute, Faculty of Science, Københavns Universitet5 Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet
a mathematical tumor control model with multiple modes of failure
As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data.
International Journal of Radiation: Oncology - Biology - Physics, 2013, Vol 87, Issue 2, p. 422-429
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Algorithms; Cerebellar Neoplasms; Child; Disease-Free Survival; Dose-Response Relationship, Radiation; Humans; Medulloblastoma; Models, Biological; Monte Carlo Method; Neoplasm Recurrence, Local; Rare Diseases; Treatment Failure; Uncertainty