a mathematical tumor control model with multiple modes of failure
As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data.
International Journal of Radiation: Oncology - Biology - Physics, 2013, Vol 87, Issue 2, p. 422-429
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Algorithms; Cerebellar Neoplasms; Child; Disease-Free Survival; Dose-Response Relationship, Radiation; Humans; Medulloblastoma; Models, Biological; Monte Carlo Method; Neoplasm Recurrence, Local; Rare Diseases; Treatment Failure; Uncertainty