Chouin, Nicolas2; Lindegren, Sture2; Frost, Sofia H L2; Jensen, Holger1; Albertsson, Per2; Hultborn, Ragnar2; Palm, Stig2; Jacobsson, Lars2; Bäck, Tom2
1 Klinik for Klinisk Fysiologi, Nuklearmedicin og PET, Diagnostisk Center, Rigshospitalet, The Capital Region of Denmark2 unknown
Targeted α-therapy (TAT) appears to be an ideal therapeutic technique for eliminating malignant circulating, minimal residual, or micrometastatic cells. These types of malignancies are typically infraclinical, complicating the evaluation of potential treatments. This study presents a method of ex vivo activity quantification with an α-camera device, allowing measurement of the activity taken up by tumor cells in biologic structures a few tens of microns.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 2013, Vol 54, Issue 8, p. 1347-53