Banzhaf, Christina Alette2; Themstrup, Lotte3; Ring, Hans Christian3; Welzel, Julia3; Mogensen, Mette4; Jemec, Gregor Borut Ernst4
1 Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet2 Department of Dermatology, Roskilde Hospital, Roskilde, Denmark.3 unknown4 Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet
BACKGROUND: Sarcoptes scabiei can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. METHODS: Five patients from the Departments of Dermatology, Augsburg, Germany, and Roskilde, Denmark, were OCT scanned (VivoSight(®); Michelson Diagnostics Ltd., UK). Mites were identified by epiluminescence and light microscopy to confirm the diagnosis. RESULTS: OCT identified S. scabiei mites in all patients in vivo. Mites and burrows were visualized, and some detail on burrow content was provided. CONCLUSION: OCT can visualize S. scabiei mites in vivo, suggesting that it may be used to study the biology of the mites in vivo and provide early assessment of scabicide therapy. OCT is able to visualize structures in the skin with an 8-μm resolution. Therefore, this technology could potentially allow rapid, non-invasive, in vivo diagnosis and analysis of infestations.
Case Reports in Dermatology, 2013, Vol 5, Issue 2, p. 156-62