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5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Authors:

Hopkinson, RJ ;
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Tumber, A ;
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Yapp, C ;
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Chowdhury, R ;
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Aik, W ;
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Che, KH ;
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Li, XS ;
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Kristensen, JBL ;
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King, ONF ;
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Chan, MC ;
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Yeoh, KK ;
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Choi, H ;
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Walport, LJ ;
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Thinnes, CC ;
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Bush, JT ;
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Lejeune, C ;
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Rydzik, AM ;
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Rose, NR ;
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Bagg, EA ;
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McDonough, MA ;
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Krojer, TJ ;
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Yue, WW ;
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Ng, SS ;
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Olsen, Lars ;
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Biostructural Research, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, Københavns Universitet
Brennan, PE ;
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Oppermann, U ;
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Muller, S ;
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Klose, RJ ;
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Ratcliffe, PJ ;
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Schofield, CJ ;
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Kawamura, A
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DOI:

10.1039/C3SC51122G

Type:

Journal article

Language:

English

Published in:

Chemical Science, 2013, Vol 4, Issue 8, p. 3110-3117

Main Research Area:

Medical science

Publication Status:

Published

Review type:

Peer Review

Submission year:

2013

Scientific Level:

Scientific

ID:

243419899