1 Arbejds- og miljømedicinsk klinik, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark2 Department of Respiratory Medicine, Medical Center, Amager and Hvidovre Hospital, The Capital Region of Denmark3 Medical Center, Amager and Hvidovre Hospital, The Capital Region of Denmark4 Copenhagen City Heart Study, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark5 Internal Medicine, Herlev, Herlev and Gentofte Hospital, The Capital Region of Denmark6 unknown
INTRODUCTION: The reduction in the ratio between forced expiratory volume in 1 s (FEV(1) ) and forced vital capacity (FVC) is used for the diagnosis of chronic obstructive pulmonary disease (COPD). The choice between a simple fixed cut-off ratio (FEV(1) /FVC LLN had well-preserved FEV(1) . CONCLUSION: Using the fixed ratio for diagnosing COPD in an epidemiological setting results in a higher prevalence than if the LLN is used. Time seems ripe for studying if the same is seen when diagnosing COPD in the clinical setting.
Clinical Respiratory Journal, 2013, Vol 7, Issue 3, p. 297-303