Risk of Inflammatory Bowel Disease following Bacille Calmette-Guérin and Smallpox Vaccination: A Population-based Danish Case-Cohort Study

Anne Marie Villumsen; Tine Jess; Signe Sørup; Henrik Ravn; Erik Sturegård; Christine Stabell Benn; Peter Aaby; Adam Anders Edvin Roth

doi:10.1097/MIB.0b013e318281f34e

Risk of Inflammatory Bowel Disease following Bacille Calmette-Guérin and Smallpox Vaccination

Authors:

Villumsen, Anne Marie ;
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Psykologisk Institut
Jess, Tine ;
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SUND ph.d. skole
Sørup, Signe ;
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Register/Ulykker/Hjerter, National Institute of Public Health, Det Sundhedsvidenskabelige Fakultet, SDU
Ravn, Henrik ;
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Institut for Klinisk Medicin
Sturegård, Erik ;
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unknown
Benn, Christine Stabell ;
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Open - Odense Patient data Explorative Network, Department of Clinical Research, Det Sundhedsvidenskabelige Fakultet, SDU
Aaby, Peter ;
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SUND ph.d. skole
Roth, Adam Anders Edvin
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Bachelor- og kandidatuddannelser

Subtitle:

A Population-based Danish Case-Cohort Study

DOI:

10.1097/MIB.0b013e318281f34e

Abstract:

Childhood immunology has been suggested to play a role in development of inflammatory bowel disease (IBD) based on the studies of childhood vaccinations, infections, and treatment with antibiotics. Bacille Calmette-Guérin (BCG) and smallpox vaccinations were gradually phased-out in Denmark for children born between 1965 and 1976, hence allowing the study of subsequent risk of Crohn's disease and ulcerative colitis in a unique prospective design.

Type:

Journal article

Language:

English

Published in:

Inflammatory Bowel Diseases, 2013, Vol 19, Issue 8, p. 1717-1724

Keywords:

Inflammatory bowel disease, bacille calmette-guérin, smallpox vaccination

Main Research Area:

Medical science

Publication Status:

Published

Review type:

Peer Review

Submission year:

2013

Scientific Level:

Scientific

ID:

242981241

Risk of Inflammatory Bowel Disease following Bacille Calmette-Guérin and Smallpox Vaccination

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