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Risk of Inflammatory Bowel Disease following Bacille Calmette-Guérin and Smallpox Vaccination

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Authors:
  • Villumsen, Anne Marie ;
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    Psykologisk Institut
  • Jess, Tine ;
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    SUND ph.d. skole
  • Sørup, Signe ;
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    Register/Ulykker/Hjerter, National Institute of Public Health, Faculty of Health Sciences, SDU
  • Ravn, Henrik ;
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    Institut for Klinisk Medicin
  • Sturegård, Erik ;
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    unknown
  • Benn, Christine Stabell ;
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    Open - Odense Patient data Explorative Network, Department of Clinical Research, Faculty of Health Sciences, SDU
  • Aaby, Peter ;
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    Open - Odense Patient data Explorative Network, Department of Clinical Research, Faculty of Health Sciences, SDU
  • Roth, Adam Anders Edvin
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    Bachelor- og kandidatuddannelser
Subtitle:
A Population-based Danish Case-Cohort Study
DOI:
10.1097/MIB.0b013e318281f34e
Abstract:
Childhood immunology has been suggested to play a role in development of inflammatory bowel disease (IBD) based on the studies of childhood vaccinations, infections, and treatment with antibiotics. Bacille Calmette-Guérin (BCG) and smallpox vaccinations were gradually phased-out in Denmark for children born between 1965 and 1976, hence allowing the study of subsequent risk of Crohn's disease and ulcerative colitis in a unique prospective design.
Type:
Journal article
Language:
English
Published in:
Inflammatory Bowel Diseases, 2013, Vol 19, Issue 8, p. 1717-1724
Keywords:
Inflammatory bowel disease, bacille calmette-guérin, smallpox vaccination
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2013
Scientific Level:
Scientific
ID:
242981241

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