Kozek-Langenecker, Sibylle A4; Afshari, Arash1; Albaladejo, Pierre4; Santullano, Cesar Aldecoa Alvarez4; De Robertis, Edoardo4; Filipescu, Daniela C4; Fries, Dietmar4; Görlinger, Klaus4; Haas, Thorsten4; Imberger, Georgina2; Jacob, Matthias4; Lancé, Marcus4; Llau, Juan4; Mallett, Sue4; Meier, Jens4; Rahe-Meyer, Niels4; Samama, Charles Marc4; Smith, Andrew4; Solomon, Cristina4; Van der Linden, Philippe4; Wikkelsø, Anne Juul3; Wouters, Patrick4; Wyffels, Piet4
1 Anaesthesiology, Department of - Juliane Marie Centre, Juliane Marie Centre, Rigshospitalet, The Capital Region of Denmark2 Copenhagen Trial Unit, Cochranecenteret Rigshospitalet, Rigshospitalet, The Capital Region of Denmark3 Anaesthesiology, Herlev, Herlev and Gentofte Hospital, The Capital Region of Denmark4 unknown
guidelines from the European Society of Anaesthesiology
The aims of severe perioperative bleeding management are three-fold. First, preoperative identification by anamesis and laboratory testing of those patients for whom the perioperative bleeding risk may be increased. Second, implementation of strategies for correcting preoperative anaemia and stabilisation of the macro- and microcirculations in order to optimise the patient's tolerance to bleeding. Third, targeted procoagulant interventions to reduce the amount of bleeding, morbidity, mortality and costs. The purpose of these guidelines is to provide an overview of current knowledge on the subject with an assessment of the quality of the evidence in order to allow anaesthetists throughout Europe to integrate this knowledge into daily patient care wherever possible. The Guidelines Committee of the European Society of Anaesthesiology (ESA) formed a task force with members of scientific subcommittees and individual expert members of the ESA. Electronic databases were searched without language restrictions from the year 2000 until 2012. These searches produced 20 664 abstracts. Relevant systematic reviews with meta-analyses, randomised controlled trials, cohort studies, case-control studies and cross-sectional surveys were selected. At the suggestion of the ESA Guideline Committee, the Scottish Intercollegiate Guidelines Network (SIGN) grading system was initially used to assess the level of evidence and to grade recommendations. During the process of guideline development, the official position of the ESA changed to favour the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. This report includes general recommendations as well as specific recommendations in various fields of surgical interventions. The final draft guideline was posted on the ESA website for four weeks and the link was sent to all ESA members. Comments were collated and the guidelines amended as appropriate. When the final draft was complete, the Guidelines Committee and ESA Board ratified the guidelines.
European Journal of Anaesthesiology, 2013, Vol 30, Issue 6, p. 270-382
Journal Article; Research Support, Non-U.S. Gov't; Review