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<sup>45</sup>Ti extraction using hydroxamate resin

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Authors:
  • Gagnon, K. ;
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    University of Alberta
  • Severin, Gregory ;
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    Orcid logo0000-0003-1189-7311
    Center for Nuclear Technologies, Technical University of Denmark
  • Barnhart, T. E. ;
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    University of Wisconsin-Madison
  • Engle, J. W. ;
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    Los Alamos National Laboratory
  • Valdovinos, H. F. ;
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    University of Wisconsin-Madison
  • Nickles, R. J.
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    University of Wisconsin-Madison
DOI:
10.1063/1.4773970
Abstract:
As an attractive radionuclide for positron emission tomography, this study explores the extraction and reactivity of 45Ti produced via the 45Sc(p,n)45Ti reaction on a GE PETtrace. Using a small hydroxamate column, we have demonstrated an overall recovery of >50% of 45Ti in ~1 mL of 1M oxalic acid. Conditions for reacting with desferal were also explored, with effective specific activities up to 38 GBq/μmol obtained.
Type:
Conference paper
Language:
English
Published in:
Aip Conference Proceedings - American Institute of Physics, 2012, Vol 1509, Issue 1, p. 211-214
Keywords:
Cyclotron; 45Ti production; Scandium; Hydroxamate resin; Desferal; Chelation; Positron emitter
Main Research Area:
Science/technology
Publication Status:
Published
Review type:
Peer Review
Conference:
14th International Workshop on Targetry and Target Chemistry, 2012
Submission year:
2013
Scientific Level:
Scientific
ID:
242895645

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