Efficacy and safety of raltegravir for treatment of HIV for 5 years in the BENCHMRK studies: final results of two randomised, placebo-controlled trials

Joseph J Eron; David A Cooper; Roy T Steigbigel; Bonaventura Clotet; Jose M Gatell; Princy N Kumar; Jurgen K Rockstroh; Mauro Schechter; Martin Markowitz; Patrick Yeni; Mona R Loutfy; Adriano Lazzarin; Jeffrey L Lennox; Kim M Strohmaier; Hong Wan; Richard Jo Barnard; Bach-Yen T Nguyen; Hedy Teppler; Court Pedersen

doi:10.1016/S1473-3099(13)70093-8

Efficacy and safety of raltegravir for treatment of HIV for 5 years in the BENCHMRK studies

Authors:

Eron, Joseph J ;
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Cooper, David A ;
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Steigbigel, Roy T ;
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Clotet, Bonaventura ;
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Gatell, Jose M ;
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Kumar, Princy N ;
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Rockstroh, Jurgen K ;
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Schechter, Mauro ;
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Markowitz, Martin ;
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Yeni, Patrick ;
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Loutfy, Mona R ;
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Lazzarin, Adriano ;
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Lennox, Jeffrey L ;
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Strohmaier, Kim M ;
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Wan, Hong ;
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Barnard, Richard Jo ;
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Nguyen, Bach-Yen T ;
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Teppler, Hedy ;
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Pedersen, Court
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Infectious Diseases, Department of Clinical Research, Faculty of Health Sciences, SDU

Subtitle:

final results of two randomised, placebo-controlled trials

DOI:

10.1016/S1473-3099(13)70093-8

Abstract:

Two randomised, placebo-controlled trials-BENCHMRK-1 and BENCHMRK-2-investigated the efficacy and safety of raltegravir, an HIV-1 integrase strand-transfer inhibitor. We report final results of BENCHMRK-1 and BENCHMRK-2 combined at 3 years (the end of the double-blind phase) and 5 years (the end of the study).

Type:

Journal article

Language:

English

Published in:

Lancet Infectious Diseases (portuguese Edition), 2013, Vol 13, Issue 7, p. 587-596

Main Research Area:

Medical science

Publication Status:

Published

Review type:

Peer Review

Submission year:

2013

Scientific Level:

Scientific

ID:

242867079

Efficacy and safety of raltegravir for treatment of HIV for 5 years in the BENCHMRK studies

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