A Cross-Sectional Survey among Urban Adults in Mwanza, Tanzania
One third of the world's population is estimated to be latently infected with Mycobacterium tuberculosis (LTBI). Surveys of LTBI are rarely performed in resource poor TB high endemic countries like Tanzania although low-income countries harbor the largest burden of the worlds LTBI. The primary objective was to estimate the prevalence of LTBI in household contacts of pulmonary TB cases and a group of apparently healthy neighborhood controls in an urban setting of such a country. Secondly we assessed potential impact of LTBI on inflammation by quantitating circulating levels of an acute phase reactant: alpha-1-acid glycoprotein (AGP) in neighborhood controls.
P L O S One, 2013, Vol 8, Issue 5
Adult; Coinfection; Cross-Sectional Studies; Female; HIV Infections; Humans; Interferon-gamma Release Tests; Latent Tuberculosis; Male; Middle Aged; Prevalence; Tanzania; Urban Population; Young Adult; Journal Article; Research Support, Non-U.S. Gov't