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Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries

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Authors:
  • Ahnstedt, Hilda ;
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    unknown
  • Cao, Lei ;
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    unknown
  • Krause, Diana N ;
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    unknown
  • Warfvinge, Karin ;
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    unknown
  • Säveland, Hans ;
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    unknown
  • Nilsson, Lars Ola ;
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    Biosystems Division
  • Edvinsson, Lars
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    Department of Clinical Medicine, Department of Clinical Medicine, Faculty of Health and Medical Sciences, Københavns Universitet
DOI:
10.1371/journal.pone.0062698
Abstract:
Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men and women differ in cerebrovascular receptor upregulation.
Type:
Journal article
Language:
English
Published in:
P L O S One, 2013, Vol 8, Issue 4
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2013
Scientific Level:
Scientific
ID:
241336306

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