Clinical (123)I-2-β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)nortropane ((123)I-FP-CIT) SPECT studies are commonly performed and reported using visual evaluation of tracer binding, an inherently subjective method. Increased objectivity can potentially be obtained using semiquantitative analysis. In this study, we assessed whether semiquantitative analysis of (123)I-FP-CIT tracer binding created more reproducible clinical reporting. A secondary aim was to determine in what form semiquantitative data should be provided to the reporter.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 2013, Vol 54, Issue 5, p. 714-22
Journal Article; Research Support, Non-U.S. Gov't; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Observer Variation; Reproducibility of Results; Research Design; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Tropanes; Young Adult