Low plasma arginine:asymmetric dimethyl arginine ratios predict mortality after intracranial aneurysm rupture
- Authors:
-
- Staalsø, Jonatan Myrup ;
- Bergström, Anita ;
- Edsen, Troels ;
- Weikop, Pia ;
- Romner, Bertil ;
-
Olsen, Niels Vidiendal
Close
0000-0001-7724-3981
Eyepath Lab, Department of Neuroscience, Faculty of Health and Medical Sciences, Københavns Universitet
- DOI:
- 10.1161/STROKEAHA.111.000605
- Abstract:
- Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthases, predicts mortality in cardiovascular disease and has been linked to cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). In this prospective study, we assessed whether circulating ADMA, arginine:ADMA ratio, and nitrite/nitrate levels were associated with survival and cerebral vasospasm in SAH patients.
- Type:
- Journal article
- Language:
- English
- Published in:
- Stroke, 2013, Vol 44, Issue 5, p. 1273-81
- Keywords:
- Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Arginine; Biological Markers; Blood Flow Velocity; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Vasospasm, Intracranial; Journal Article; Research Support, Non-U.S. Gov't
- Main Research Area:
- Medical science
- Publication Status:
- Published
- Review type:
- Peer Review
- Submission year:
- 2013
- Scientific Level:
- Scientific
- ID:
- 240908306
