Treatment of anemia with darbepoetin alfa in systolic heart failure

Karl Swedberg; James B Young; Inder S Anand; Sunfa Cheng; Akshay S Desai; Rafael Diaz; Aldo P Maggioni; John J V McMurray; Christopher O'Connor; Marc A Pfeffer; Scott D Solomon; Hong Yan Sun; Michal Tendera; Dirk J van Veldhuisen; Jens Erik Rokkedal Nielsen

doi:10.1056/NEJMoa1214865

Treatment of anemia with darbepoetin alfa in systolic heart failure

Authors:

Swedberg, Karl ;
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University of Gothenburg
Young, James B ;
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unknown
Anand, Inder S ;
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unknown
Cheng, Sunfa ;
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unknown
Desai, Akshay S ;
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unknown
Diaz, Rafael ;
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unknown
Maggioni, Aldo P ;
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unknown
McMurray, John J V ;
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unknown
O'Connor, Christopher ;
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unknown
Pfeffer, Marc A ;
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unknown
Solomon, Scott D ;
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unknown
Sun, Hong Yan ;
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Department of Control and Engineering Design
Tendera, Michal ;
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unknown
van Veldhuisen, Dirk J ;
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unknown
Nielsen, Jens Erik Rokkedal
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Medicine Glostrup, Department of, Amager and Hvidovre Hospital, The Capital Region of Denmark

DOI:

10.1056/NEJMoa1214865

Abstract:

Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia.

Type:

Journal article

Language:

English

Published in:

New England Journal of Medicine, 2013, Vol 368, Issue 13, p. 1210-9

Keywords:

Aged; Anemia; Double-Blind Method; Erythropoietin; Female; Heart Failure, Systolic; Hematinics; Hemoglobins; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Shock, Septic; Stroke; Thromboembolism; Treatment Failure; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Main Research Area:

Medical science

Publication Status:

Published

Review type:

Peer Review

Submission year:

2013

Scientific Level:

Scientific

ID:

240271600

Treatment of anemia with darbepoetin alfa in systolic heart failure

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