While certain inherited syndromes (e.g. Neurofibromatosis or Li-Fraumeni) are associated with an increased risk of glioma, most familial gliomas are non-syndromic. This study describes the demographic and clinical characteristics of the largest series of non-syndromic glioma families ascertained from 14 centres in the United States (US), Europe and Israel as part of the Gliogene Consortium.
European Journal of Cancer (oxford, England : 1990), 2013, Vol 49, Issue 6, p. 1335-45
Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Child, Preschool; Denmark; Family Health; Female; Glioma; Humans; Incidence; Infant; Israel; Male; Middle Aged; Neoplasm Grading; Pedigree; Prevalence; Sex Factors; Sweden; United States; Young Adult; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't