Hereditary angioedema due to C1-inhibitor deficiency (HAE-C1-INH) causes disturbances in the complement system. However, the influence of HAE-C1-INH on the lectin pathway of complement is unresolved. Thus, we studied the main initiator molecules, enzymes and regulators in the lectin pathway in patients with HAE-C1-INH.
Molecular Immunology, 2013, Vol 54, Issue 3-4, p. 271-277
Journal Article; Research Support, Non-U.S. Gov't; Adaptor Proteins, Signal Transducing; Adult; Aged; Apoptosis Regulatory Proteins; Case-Control Studies; Complement C1 Inhibitor Protein; Complement Pathway, Mannose-Binding Lectin; Female; Glycoproteins; Hereditary Angioedema Types I and II; Humans; Lectins; Male; Mannose-Binding Protein-Associated Serine Proteases; Middle Aged; Young Adult