Aarestrup, Frank Møller1; Brown, Eric W4; Detter, Chris4; Gerner-Smidt, Peter4; Gilmour, Matthew W4; Harmsen, Dag4; Hendriksen, Rene S.1; Hewson, Roger4; Heymann, David L4; Johansson, Karin4; Ijaz, Kashef4; Keim, Paul S4; Koopmans, Marion4; Kroneman, Annelies4; Wong, Danilo Lo Fo1; Lund, Ole4; Palm, Daniel4; Sawanpanyalert, Pathom4; Sobel, Jeremy4; Schlundt, Jørgen1
1 National Food Institute, Technical University of Denmark2 Division of Epidemiology and Microbial Genomics, National Food Institute, Technical University of Denmark3 Communications and Management Secretariat, National Food Institute, Technical University of Denmark4 unknown
The rapid advancement of genome technologies holds great promise for improving the quality and speed of clinical and public health laboratory investigations and for decreasing their cost. The latest generation of genome DNA sequencers can provide highly detailed and robust information on disease-causing microbes, and in the near future these technologies will be suitable for routine use in national, regional, and global public health laboratories. With additional improvements in instrumentation, these next- or third-generation sequencers are likely to replace conventional culture-based and molecular typing methods to provide point-of-care clinical diagnosis and other essential information for quicker and better treatment of patients. Provided there is free-sharing of information by all clinical and public health laboratories, these genomic tools could spawn a global system of linked databases of pathogen genomes that would ensure more efficient detection, prevention, and control of endemic, emerging, and other infectious disease outbreaks worldwide.