Transcranial magnetic stimulation (TMS) commonly uses so-called monophasic pulses where the initial rapidly changing current flow is followed by a critically dampened return current. It has been shown that a monophasic TMS pulse preferentially excites different cortical circuits in the human motor hand area (M1-HAND), if the induced tissue current has a posterior-to-anterior (PA) or anterior-to-posterior (AP) direction. Here we tested whether similar direction-specific effects could be elicited in M1-HAND using TMS pulses with a half-sine wave configuration.
Bmc Neuroscience, 2012, Vol 13, Issue 1
Biophysics; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Female; Hand; Humans; Male; Motor Cortex; Muscle, Skeletal; Reaction Time; Transcranial Magnetic Stimulation; Journal Article; Research Support, Non-U.S. Gov't