Shapiro, Michael D.9; Kronenberg, Zev9; Li, Cai10; Domyan, Eric T.9; Pan, Hailin6; Campbell, Michael9; Tan, Hao6; Huff, Chad D.9; Hu, Haofu6; Vickrey, Anna I.9; Nielsen, Sandra Cathrine Abel11; Stringham, Sydney A.9; Hu, Hao12; Willerslev, Eske10; Gilbert, M Thomas P10; Yandell, Mark9; Zhang, Guojie6; Wang, Jun13
1 Natural History Museum of Denmark, Faculty of Science, Københavns Universitet2 Natural History Museum of Denmark, Natural History Museum of Denmark, Faculty of Science, Københavns Universitet3 Section for Metabolic Genetics, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, Københavns Universitet4 Genome Research and Molecular Bio Medicine, Department of Biology, Faculty of Science, Københavns Universitet5 University of Utah6 BGI-Shenzhen7 University of Texas M. D. Anderson Cancer Center8 Department of Biology, Faculty of Science, Københavns Universitet9 University of Utah10 Natural History Museum of Denmark, Natural History Museum of Denmark, Faculty of Science, Københavns Universitet11 Natural History Museum of Denmark, Faculty of Science, Københavns Universitet12 University of Texas M. D. Anderson Cancer Center13 Department of Biology, Faculty of Science, Københavns Universitet
The geographic origins of breeds and the genetic basis of variation within the widely distributed and phenotypically diverse domestic rock pigeon (Columba livia) remain largely unknown. We generated a rock pigeon reference genome and additional genome sequences representing domestic and feral populations. We found evidence for the origins of major breed groups in the Middle East and contributions from a racing breed to North American feral populations. We identified the gene EphB2 as a strong candidate for the derived head crest phenotype shared by numerous breeds, an important trait in mate selection in many avian species. We also found evidence that this trait evolved just once and spread throughout the species, and that the crest originates early in development by the localized molecular reversal of feather bud polarity.
Science (new York, N.y.), 2013, Vol 339, Issue 6123, p. 1063-1067