Diabetes increases the risk of cardiovascular complications including arrhythmias, but the underlying mechanisms remain to be established. Decreased conduction velocity (CV), which is an independent risk factor for re-entry arrhythmias, is present in models with streptozotocin (STZ) induced type 1 diabetes. Whether CV is also disturbed in models of type 2 diabetes is currently unknown.
Cardiovascular Diabetology, 2013, Vol 12
Animals; Diabetes Mellitus, Type 2; Heart; Heart Conduction System; Heart Ventricles; Male; Myocardium; Organ Culture Techniques; Rats; Rats, Zucker; Journal Article; Research Support, Non-U.S. Gov't