Photoentrainment of circadian rhythm begins with the stimulation of melanopsin containing retinal ganglion cells that respond directly to blue light. With age, the human lens becomes a strong colour filter attenuating transmission of short wavelengths. The purpose of the study was to examine the effect the ageing human lens may have for the photoentrainment of circadian rhythm and to compare with intraocular implant lenses (IOLs) designed to block UV radiation, violet or blue light.
Acta Ophthalmologica (online), 2013, Vol 91, Issue 1, p. 52-7
Journal Article; Research Support, Non-U.S. Gov't; Adolescent; Adult; Aged; Aging; Circadian Rhythm; Filtration; Humans; Lens, Crystalline; Lenses, Intraocular; Light; Melatonin; Middle Aged; Photoperiod; Pupil; Radio Waves; Retinal Pigment Epithelium; Rod Opsins; Tissue Donors; Young Adult